| Transactions |
| Date | Team | Player | Type | OthTm | EffDate | When |
| 5/18/1964 | KCA | Coleman,J | Demoted to reserve roster |   |   | Before |
| 6/3/1964 | CAA | Bertaina | Demoted to reserve roster |   |   | Before |
| 6/8/1964 | CWS | Lindblad | Demoted to reserve roster |   |   | Before |
| 6/12/1964 | CAA | Hiller,J | Demoted to reserve roster |   |   | Before |
| 6/12/1964 | CLE | Agee | Demoted to reserve roster |   |   | Before |
| 6/15/1964 | WAS | Piche | Demoted to reserve roster |   |   | Before |
| 6/18/1964 | | Ray | Acquired via trade | NYM |   | After |
| 6/22/1964 | NYY | Zachary | Demoted to reserve roster |   |   | Before |
| 6/22/1964 | WAS | Tartabull | Demoted to reserve roster |   |   | Before |
| 7/15/1964 | BAL | Etchebarren | Demoted to reserve roster |   |   | Before |
| 7/15/1964 | CWS | Hoerner | Demoted to reserve roster |   |   | Before |
| 7/15/1964 | KCA | Pierce | Demoted to reserve roster |   |   | Before |
| 7/20/1964 | KCA | Nischwitz | Signed |   |   | Before |
| 7/20/1964 | KCA | Parsons | Released |   |   | Before |
| 7/20/1964 | KCA | Parsons | Signed |   |   | Before |
| 7/22/1964 | BAL | Peterson | Demoted to reserve roster |   |   | Before |
| 7/22/1964 | CAA | Blanchard | Demoted to reserve roster |   |   | Before |
| 7/24/1964 | CAA | Casanova | Demoted to reserve roster |   |   | Before |
| 7/27/1964 | CAA | Carreon | Signed |   |   | Before |
| 7/27/1964 | CLE | Davenport | Demoted to reserve roster |   |   | Before |
| 7/31/1964 | CLE | Davenport | Demoted to reserve roster |   |   | Before |
| 7/31/1964 | CLE | Davenport | Promoted to active roster |   |   | Before |
| 8/3/1964 | BOS | Hunter | Demoted to reserve roster |   |   | Before |
| 8/3/1964 | BOS | Rudolph | Signed |   |   | Before |
| 8/5/1964 | CWS | Larsen | Demoted to reserve roster |   |   | Before |
| 8/5/1964 | WAS | Dennis | Demoted to reserve roster |   |   | Before |
| 8/7/1964 | KCA | Fox,N | Demoted to reserve roster |   |   | Before |
| 8/7/1964 | KCA | Pleis | Signed |   |   | Before |
| 8/7/1964 | KCA | Pleis | Demoted to reserve roster |   |   | Before |
| 8/7/1964 | MIN | Pearson | Demoted to reserve roster |   |   | Before |
| 8/10/1964 | WAS | Hamlin | Demoted to reserve roster |   |   | Before |
| 8/12/1964 | WAS | Jones,D | Demoted to reserve roster |   |   | Before |
| 8/12/1964 | WAS | Nossek | Demoted to reserve roster |   |   | Before |
| 8/14/1964 | BAL | Lau | Demoted to reserve roster |   |   | Before |
| 8/14/1964 | CAA | Belinsky | Demoted to reserve roster |   |   | Before |
| 8/14/1964 | WAS | Kekich | Released |   |   | Before |
| 8/14/1964 | WAS | Kekich | Signed |   |   | Before |
| 8/17/1964 | BAL | Stephenson,Jo | Signed |   |   | Before |
| 8/17/1964 | BOS | Carroll | Promoted to active roster |   |   | Before |
| 8/17/1964 | BOS | McCool | Demoted to reserve roster |   |   | Before |
| 8/17/1964 | CLE | Singer | Promoted to active roster |   |   | Before |
| 8/17/1964 | CLE | Tiant | Demoted to reserve roster |   |   | Before |
| 8/17/1964 | KCA | Pleis | Promoted to active roster |   |   | Before |
| 8/17/1964 | MIN | Goossen | Signed |   |   | Before |
| 8/17/1964 | WAS | Donovan | Demoted to reserve roster |   |   | Before |
| 8/19/1964 | NYY | Kostro | Demoted to reserve roster |   |   | Before |
| 8/21/1964 | NYY | Horton,T | Demoted to reserve roster |   |   | Before |
| 8/21/1964 | WAS | Sutherland | Demoted to reserve roster |   |   | Before |
| 8/24/1964 | CLE | Warwick | Signed |   |   | Before |
| 8/24/1964 | CLE | Zimmer | Demoted to reserve roster |   |   | Before |
| 8/24/1964 | DET | White,R | Demoted to reserve roster |   |   | Before |
| 8/24/1964 | WAS | LeJohn | Demoted to reserve roster |   |   | Before |
| 8/26/1964 | BAL | Estrada | Demoted to reserve roster |   |   | Before |
| 8/26/1964 | CLE | Davenport | Promoted to active roster |   |   | Before |
| 8/26/1964 | WAS | Jackson,S | Demoted to reserve roster |   |   | Before |
| 8/28/1964 | KCA | Coombs | Signed |   |   | Before |
| 8/28/1964 | KCA | Malzone | Demoted to reserve roster |   |   | Before |
| 8/31/1964 | BAL | Parsons | Signed |   |   | Before |
| 8/31/1964 | CLE | Davenport | Demoted to reserve roster |   |   | Before |
| 8/31/1964 | CLE | Malzone | Signed |   |   | Before |
| 8/31/1964 | CLE | Warwick | Demoted to reserve roster |   |   | Before |
| 8/31/1964 | KCA | Coombs | Demoted to reserve roster |   |   | Before |
| 8/31/1964 | WAS | Boccabella | Demoted to reserve roster |   |   | Before |
| 9/2/1964 | WAS | Morton | Demoted to reserve roster |   |   | Before |
| 9/2/1964 | WAS | Powell | Demoted to reserve roster |   |   | Before |
| 9/4/1964 | BOS | Alomar | Demoted to reserve roster |   |   | Before |
| 9/4/1964 | CAA | Dierker | Demoted to reserve roster |   |   | Before |
| 9/4/1964 | WAS | Clinton | Demoted to reserve roster |   |   | Before |
| 9/4/1964 | WAS | Cottier | Signed |   |   | Before |
| 9/4/1964 | WAS | Goryl | Demoted to reserve roster |   |   | Before |
| 9/4/1964 | WAS | Hardy | Signed |   |   | Before |
| 9/4/1964 | WAS | Smith,A | Signed |   |   | Before |
| 9/7/1964 | BOS | Power | Signed |   |   | Before |
| 9/7/1964 | NYY | Gibbon | Demoted to reserve roster |   |   | Before |
| 9/7/1964 | WAS | Cisco | Demoted to reserve roster |   |   | Before |
| 9/9/1964 | CAA | Bowsfield | Demoted to reserve roster |   |   | Before |
| 9/14/1964 | BAL | Stephens | Demoted to reserve roster |   |   | Before |
| 9/14/1964 | CAA | Purdin | Signed |   |   | Before |
| 9/14/1964 | CLE | Davenport | Promoted to active roster |   |   | Before |
| 9/14/1964 | CLE | Tiant | Promoted to active roster |   |   | Before |
| 9/14/1964 | DET | Green,L | Demoted to reserve roster |   |   | Before |
| 9/16/1964 | NYY | Terry | Demoted to reserve roster |   |   | Before |
| 9/18/1964 | BOS | Brown,H | Demoted to reserve roster |   |   | Before |
| 9/18/1964 | CAA | Carreon | Demoted to reserve roster |   |   | Before |
| 9/18/1964 | CAA | McCraw | Demoted to reserve roster |   |   | Before |
| 9/21/1964 | BOS | Daniels | Demoted to reserve roster |   |   | Before |
| 9/21/1964 | WAS | Sparma | Demoted to reserve roster |   |   | Before |
| 9/23/1964 | BOS | Scheinblum | Signed |   |   | Before |
| 9/23/1964 | BOS | Scheinblum | Demoted to reserve roster |   |   | Before |
| 9/23/1964 | MIN | King | Demoted to reserve roster |   |   | Before |
| 9/23/1964 | WAS | Meyer | Demoted to reserve roster |   |   | Before |
| 9/25/1964 | CLE | Maris | Demoted to reserve roster |   |   | Before |
| 9/25/1964 | KCA | Moore,B | Signed |   |   | Before |
| 9/25/1964 | KCA | Moore,B | Demoted to reserve roster |   |   | Before |
| 9/25/1964 | KCA | Pleis | Demoted to reserve roster |   |   | Before |
| 9/25/1964 | MIN | Crawford | Demoted to reserve roster |   |   | Before |
| 9/25/1964 | NYY | Gilliam | Demoted to reserve roster |   |   | Before |
| 9/25/1964 | NYY | Nottebart | Demoted to reserve roster |   |   | Before |
| 9/28/1964 | CLE | Pavletich | Demoted to reserve roster |   |   | Before |
| 9/28/1964 | DET | Green,L | Promoted to active roster |   |   | Before |
| 9/28/1964 | DET | White,R | Promoted to active roster |   |   | Before |
| 9/28/1964 | NYY | Nixon | Demoted to reserve roster |   |   | Before |
| 9/28/1964 | WAS | Haddix | Demoted to reserve roster |   |   | Before |
| 9/28/1964 | WAS | Hobbie | Signed |   |   | Before |
| 9/28/1964 | WAS | Horton,W | Demoted to reserve roster |   |   | Before |
| 9/28/1964 | WAS | Kelley,T | Demoted to reserve roster |   |   | Before |
| 9/28/1964 | WAS | McBride | Signed |   |   | Before |
| 9/28/1964 | WAS | Meyer | Released |   |   | Before |
| 9/30/1964 | CAA | Lee,B | Demoted to reserve roster |   |   | Before |
| 9/30/1964 | CAA | Purdin | Demoted to reserve roster |   |   | Before |
| 9/30/1964 | KCA | de la Hoz | Demoted to reserve roster |   |   | Before |
| 10/2/1964 | BAL | Herrnstein | Demoted to reserve roster |   |   | Before |
| 10/2/1964 | BOS | Carroll | Demoted to reserve roster |   |   | Before |
| 10/2/1964 | CLE | Cimino | Promoted to active roster |   |   | Before |
| 10/2/1964 | CLE | Reese | Promoted to active roster |   |   | Before |
| 10/2/1964 | CLE | Ribant | Demoted to reserve roster |   |   | Before |
| 10/2/1964 | CLE | Siebern | Demoted to reserve roster |   |   | Before |
| 10/2/1964 | DET | Adcock | Demoted to reserve roster |   |   | Before |
| 10/2/1964 | KCA | Nuxhall | Demoted to reserve roster |   |   | Before |
| 10/2/1964 | WAS | Henry,B | Demoted to reserve roster |   |   | Before |